Hao N, Nayak S, Behar M, Shanks RH, Nagiec MJ, Errede B,
Hasty J, Elston TC, Dohlman HG
2008. Regulation of cell signaling dynamics by the protein
kinase-scaffold Ste5.
Moll. Cell 30
(5):649-56
(Pubmed)
Violin JD, Dipilato LM, Yildirim N, Elston TC, Zhang J,
Lefkowitz
RJ.
Elston. 2008. Beta 2-adrenergic receptor signaling and desensitization
elucidated by quantitative modeling of real-time camp dynamics.
J. Biol. Chem. 283:2949-61
(Pubmed)
Wang X., Errede B., Elston T. C.
Elston. 2008. Mathematical Analysis and Quantification of Fluorescent
Proteins as Transcriptional Reporters
Biophysical Journal
94:2017-26
(Pubmed)
Kapustina M, Weinreb GE, Costigliola N, Rajfur Z, Jacobson K,
Elston TC. 2008. Mechanical and biochemical modeling of cortical
oscillations in spreading cells
Biophysical Journal
94:4605-20
(Pubmed)
Behar,
M., H. G. Dohlman, and T. C.
Elston. 2007.
Kinetic insulation as an effective mechanism for achieving pathway
specificity in intracellular signaling networks. PNAS104:16146-16151.
(Pubmed)
Guido NJ, Lee P, Wang X, Elston TC, Collins JJ. 2007. A
pathway and genetic factors contributing to elevated gene expression
noise in stationary phase.
Biophys. J. 93:L55-7
(Pubmed)
Behar,
M., N. Hao, H. G. Dohlman, and T. C.
Elston. 2007.
Mathematical and Computational Analysis of Adaptation via Feedback
Inhibition in Signal Transduction Pathways. Biophysical
Journal93:806-821.
(Pubmed)
Hao,
N., M. Behar, T. C. Elston, and H. G. Dohlman. 2007.
Systems biology analysis of G protein and MAP kinase signaling in
yeast. Oncogene
26:3254-3266. (Pubmed)
Hao,
N., M. Behar, S. C. Parnell, M. P. Torres, C. H.
Borchers, T. C. Elston, and H. G. Dohlman. 2007. A systems-biology
analysis of feedback inhibition in the sho1 osmotic-stress-response
pathway. Curr Biol17:659-667. (PubMed)
Erban,
R., T. A. Frewen, X. Wang, T. C. Elston, R. Coifman,
B. Nadler, and I. G. Kevrekidis. 2007. Variable-free exploration of
stochastic models: A gene regulatory network example. J Chem
Phys126:155103.
(PubMed)
Serohijos,
A. W., Y. Chen, F. Ding, T. C. Elston, and N. V.
Dokholyan. 2006. A structural model reveals energy transduction in
dynein. Proc Natl Acad Sci U S A103:18540-18545. (PubMed)
Wang,
X., N. Hao, H. G. Dohlman, and T. C. Elston. 2006.
Bistability, stochasticity, and oscillations in the mitogen-activated
protein kinase cascade. Biophys J90:1961-1978.(PubMed)
Guido,
N. J., X. Wang, D. Adalsteinsson, D. McMillen, J.
Hasty, C. R. Cantor, T. C. Elston, and J. J. Collins. 2006. A bottom-up
approach to gene regulation. Nature439:856-860. (PubMed)
Fricks,
J., H. Wang, and T. C. Elston. 2006. A numerical
algorithm for investigating the role of the motor-cargo linkage in
molecular motor-driven transport. J Theor Biol239:33-48. (PubMed)
Weinreb,
G. E., T. C. Elston, and K. Jacobson. 2006. Causal
mapping as a tool to mechanistically interpret phenomena in cell
motility: application to cortical oscillations in spreading cells. Cell
Motil Cytoskeleton63:523-532.
(PubMed)
Erban,
R., I. G. Kevrekidis, D. Adalsteinsson, and T. C.
Elston. 2006. Gene regulatory networks: A coarse-grained, equation-free
approach to multiscale computation. J Chem Phys124:084106.
(PubMed)
Kaern,
M., W. Blake, T.C. Elston and J. Collins. 2005.
Stochasticity in gene expression. Nat. Gen., 6
:451-464. (PubMed)
Pirone,
J. and T. Elston. 2004. Fluctuations in
transcription factor binding can explain the graded and binary
responses observed in inducible gene expression. J. Theor.
Biol.226
:111-121. (PubMed)
Adalsteinsson,
D., D. McMillen, and T.C. Elston. 2004.
Biochemical Network Stochastic Simulator (BioNetS): software for
stochastic modeling of biochemical networks. BMC
Bioinformatics5:2-37.
(PubMed)
Yildirim,
N., N. Hao, H. Dohlman, and T.C. Elston.
2004.Mathematical Modeling of RGS and G Protein Regulation in Yeast. Meth.
in Enzym. 389:383-398.
(PubMed)
Goedecke,
M. and T.C. Elston. 2004. A mechanism for the
oscillatory behavior of single dynein molecules. J. Theor.
Biol. 232:27-39.
(PubMed)
Hao,
N., Yildirim, N. Wang, Y., Elston, T.C., and
Dohlman, H.G.2003. Regulators of G protein signaling and transient
activation of signaling: Experimental and computation analysis reveals
negative and positive feedback controls on G protein activity. J.
Biol. Chem.278:46506-46515. (PubMed)
Morgan,
K., W. Casey, M. Easton, D. Creech, H. Ni, L.
Yoon, S.Anderson, C. Qualls, L. Crosby, P. Bloomfield, A.
MacPherson, and T. Elston. 2003. Frequent sampling reveals dynamic
responses by the transcriptome to routine media replacement in HepG2
cells. Tox. Path.31:448-461. (PubMed)
Wang,
H. C. Peskin, and T. Elston. 2003. A robust
numerical algorithm for studying biomolecular transport processes. J.
Theor. Biol.221:491-511.
(PDF version) (m-files)
Elston, T. 2002. The Brownian ratchet and power
stroke
models for post-translational protein translocation into the
endoplasmic reticulum. Biophys. J.82:
1239-1253. (PDF
version)
Mogilner,
A. T. Elston, H. Wang, and G.
Oster. 2002. Molecular motors: theory. In
Computational Cell Biology, C.Fall,E. Marland, J.
Tyson, and J. Wagner, Eds. (Springer,
NY). (PDF
version)
Mogilner, A. T.
Elston, H. Wang, and G.
Oster. 2002. Molecular motors: examples.
In Computational Cell Biology, C. Fall,E.
Marland, J. Tyson and J. Wagner, Eds. (Springer,
NY).
(PDF version)
Elston, T.
and T. Kepler. 2001. A Linear
Two-State Model with Complex Dynamics. PLA. 280:204-208. (PDF
version)
Elston,
T. and C. Peskin. 2000. The
role of
protein flexibility in molecular motor function: coupled
diffusion in a tilted
periodic potential. SIAM60:
842-867.(PDFversion)
Elston, T., D. You and C. Peskin.
2000.
Protein flexibility and the correlation ratchet. SIAM61: 776-791. (PDF
version)
Elston,
T. 2000. A macroscopic description of
biomolecular transport. J. Math. Biol. 41:
189-206. (PDF
version)
Elston,
T. 2000. Models of posttranslational
protein translocation. Biophys.J. 79:
2235-2251.
(PDF version)